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152154 In the classical pathway, hepatocellular SIRT1 deacetylates FOXO1 105 and FOXO3a, 155 inducing expression of autophagy-related proteins such as Atg5, Atg7, and Beclin-1, which promote autophagosome formation and maturation

Inflammatory Markers: Include CRP and homocysteine to measure systemic inflammation levels